PREDIABETES PATIENTS WITH ACUTE CORONARY SYNDROME AND HOSPITAL CLINICAL OUTCOME

Authors

  • EMAN ABDULLAHAL-SHORBAGY
  • GEHANABDEL–KADER IBRAHIM
  • MOHAMED S. S. SAAD
  • KHALED BASHIR SALEM HARSHA

Keywords:

ACUTE CORONARY SYNDROME; CORONARY COMPLICATIONS; PREDIABETES

Abstract

BACKGROUND: PREDIABETES IS COMMON IN PATIENTS PRESENTING WITH ACS WHO ARE NOT PREVIOUSLY KNOWN TO HAVE DIABETES. PREDIABETIC PATIENTS HAD WORSE IN-HOSPITAL CLINICAL OUTCOMES COMPARED WITH PATIENTS WITHOUT DIABETES. THE AIM OF THE STUDY WAS TO EXPLORE THE RELATION PREDIABETES PATIENTS WITH ACUTE CORONARY SYNDROMES THE IN-HOSPITAL CLINICAL OUTCOMES.

PATIENTS AND METHODS: THIS PROSPECTIVE STUDY WAS CONDUCTED ON 60 PATIENTS WITH ACUTE CORONARY SYNDROME WHO ADMITTED TO THE INTENSIVE CARE UNIT (ICU), INTERNAL MEDICINE DEPARTMENT, FACULTY OF MEDICINE, ZAGAZIG UNIVERSITY DURING THE PERIOD FROM SEPTEMBER 2019 TO MARCH 2020. ALL STUDIED SUBJECTS WERE SUBJECTED TO FULL HISTORY TAKING COMPLETE CLINICAL EXAMINATION, COMPLETE BLOOD COUNT, GLYCOSYLATED HAEMOGLOBIN (HBA1C), LIPID PROFILE, SERUM CREATININE AND ORAL GLUCOSE TOLERANCE TEST (OGTT), ECG AND ECHO.

RESULTS: THERE WAS A STATISTICAL SIGNIFICANT DIFFERENCE BETWEEN THE STUDIED GROUPS REGARDING ACUTE CORONARY SYNDROME TYPES, GLYCATED HAEMOGLOBIN (HBA1C), SERUM CREATININE, AND HIGH-DENSITY LIPOPROTEINS. CHOLESTEROL. THERE WAS STATISTICALLY SIGNIFICANT DIFFERENCE BETWEEN THE STUDIED PATIENTS GROUPED ACCORDING TO THE CLINICAL OUTCOME REGARDING ACS TYPES.

CONCLUSION: PRE-DIABETIC PATIENTS HAD WORSE IN-HOSPITAL CLINICAL OUTCOMES COMPARED WITH PATIENTS WITHOUT DIABETES. PRE-DIABETIC PATIENTS WITH ACS HAVE GREATER PREVALENCE OF CARDIOMETABOLIC RISK FACTORS (ABDOMINAL OBESITY, AND HYPERTENSION) AS COMPARED TO NON-DIABETIC PATIENTS.

Downloads

Download data is not yet available.

References

- LEON BM, MADDOX TM. DIABETES AND CARDIOVASCULAR DISEASE: EPIDEMIOLOGY, BIOLOGICAL MECHANISMS, TREATMENT RECOMMENDATIONS AND FUTURE RESEARCH. WORLD J DIABETES 2015; 6 (13): 1246-1258.

- ABU SHADY MM, MOHAMADY Y, ENANY B, NAMMAS W. PREVALENCE OF PREDIABETES IN PATIENTS WITH ACUTE CORONARY SYNDROME: IMPACT ON IN-HOSPITAL OUTCOMES. INTERN MED J. 2015; 45(2): 183–188.

- NORHAMMAR A, TENERZ A, NILSSON G, HAMSTEN A, EFENDÍC S, RYDÉN L ET AL. GLUCOSE METABOLISM IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION AND NO PREVIOUS DIAGNOSIS OF DIABETES MELLITUS: A PROSPECTIVE STUDY. LANCET 2002; 359 (9324): 2140-2144.

- CAPES SE, HUNT D, MALMBERG K, GERSTEIN HC. STRESS HYPERGLYCAEMIA AND INCREASED RISK OF DEATH AFTER MYOCARDIAL SYSTEMATIC INFARCTIONINPATIENTS WITH AND WITH OUT DIABETES: AN OVER VIEW. LANCET 2000; 355 (9206) : 773–778.

- WILD S, ROGLIC G, GREEN A, SICREE R, KING H. GLOBAL PREVENTION OF DIABETES: ESTIMATES FOR THE YEAR 2000 AND PROJECTIONS FOR 2030. DIABETES CARE 2004; 27(5):1047-1053.

- ZETHELIUS B, HALES CN, BERNE C. INSULIN RESISTANCE, PROINSULIN AND CORONARY HEART DISEASE: A POPULATION-BASED, FOLLOW-UP STUDY IN 70-YEAR-OLD MEN USING EUGLYCAEMIC INSULIN CLAMP. DIABETOLOGIA 2004; 47 (1):A42.

- PANDURANGA P, SULAIMAN K, AL-LAWATI J, AL-ZAKWANI I. RELATIONSHIP BETWEEN ADMITTING NONFASTING BLOOD GLUCOSE AND IN-HOSPITAL MORTALITY STRATIFIED BY DIABETES MELLITUS AMONG ACUTE CORONARY SYNDROME PATIENTS IN OMAN. HEART VIEWS 2011; 12 (1): 12-17.

- SOUSA AC, PINHEIRO CP, OLIVEIRA MD, FARO GB, SILVA EC, ROCHA EA ET AL. PROGNOSTIC VALUE OF STRESS HYPERGLYCEMIA FOR IN-HOSPITAL OUTCOME IN ACUTE CORONARY ARTERY DISEASE. ARQ BRAS CARDIOL. 2013; 100 (2):127-34.

- AÇAR B, OZEKE O, KARAKURT M, OZEN Y, ÖZBAY M, UNAL S ET AL. ASSOCIATION OF PREDIABETES WITH HIGHER CORONARY ATHEROSCLEROTIC BURDEN AMONG PATIENTS WITH FIRST DIAGNOSED ACUTE CORONARY SYNDROME. ANGIOLOGY 2019; 70 (2) : 174-180.

- CUEVA-RECALDE JF, RUIZ-ARROYO JR, GARCÍA-BLANCO FR. PREDIABETES AND CORONARY ARTERY DISEASE: OUTCOME AFTER REVASCULARIZATION PROCEDURES. ENDOCRINOL NUTR 2016; 63 (3):106-112.

- ZHOU M, LIU J, HAO Y, LIU J, HUO Y, SMITH S ET AL. PREVALENCE AND IN-HOSPITAL OUTCOMES OF DIABETES AMONG PATIENTS WITH ACUTE CORONARY SYNDROME IN CHINA: FINDINGS FROM THE IMPROVING CARE FOR CARDIOVASCULAR DISEASE IN CHINA-ACUTE CORONARY SYNDROME PROJECT. CARDIOVASC DIABETOL 2018; 17(1): 147.

- MIRGHANI HO, MOHAMMED OS, ALYOUSSUF AA. OUTCOMES OF PREDIABETES AND UNDISCOVERED DIABETES AMONG PATIENTS WITH ACUTE CORONARY SYNDROME. J TAIBAH UNIV MED SCI 2016, 11(4), 359-363.

Downloads

Published

2021-10-30

How to Cite

ABDULLAHAL-SHORBAGY, E. ., IBRAHIM, G. ., SAAD, M. S. S. . ., & HARSHA, K. B. S. . (2021). PREDIABETES PATIENTS WITH ACUTE CORONARY SYNDROME AND HOSPITAL CLINICAL OUTCOME. The Journal of Contemporary Issues in Business and Government, 27(5), 2768–2775. Retrieved from https://cibgp.com/au/index.php/1323-6903/article/view/2147