Assessment of risk factor for oral submucous fibrosis in patients- a retrospective study
Keywords:
Oral submucous fibrosis; Pan chewing; Risk factor; Tobacco smokingAbstract
Oral submucous fibrosis(OSMF) is a precancerous condition progessive disorder which is caused because of the tobacco products usage,consumption of spicy foods.It will cause rigidity of the tongue,lip and palate in the severe cases it will cause limited mouth opening.Parts which gets affected will be oral cavity,pharynx and upper third of esophagus.This study is done to assess risk factor oral submucous fibrosis (OSMF) in patients getting treated in saveetha dental college and hospitals.A retrospective study was conducted in dental hospitals in departments of oral and maxillofacial surgery,department of oral medicine.Patient data was collected from hospital records.In our study we found that use of tobacco smoking (31.2%),pan chewing(34.4%),Tobacco chewing(23.7%), and betel nut chewing(9.7%).Total sample size(n=93) 7 female patients ,86 male patients.Most affected age group will be (41-50 years old)-26.9%.Our study pan chewing and tobacco products among the 41-50 years old male population were significantly high in association with the risk factor of OSMF.
References
Abhinav, R. P. et al. (2019) ‘The Patterns and Etiology of Maxillofacial Trauma in South India’, Annals of maxillofacial surgery, 9(1), pp. 114–117.
Ahmad, M. S. et al. (2006) ‘Epidemiological and etiological study of oral submucous fibrosis among gutkha chewers of Patna, Bihar, India’, Journal of the Indian Society of Pedodontics and Preventive Dentistry, 24(2), pp. 84–89.
Christabel, A. et al. (2016) ‘Comparison of pterygomaxillary dysjunction with tuberosity separation in isolated Le Fort I osteotomies: a prospective, multi-centre, triple-blind, randomized controlled trial’, International Journal of Oral and Maxillofacial Surgery, pp. 180–185. doi: 10.1016/j.ijom.2015.07.021.
Das, S. (2014) ‘FRI-06 SUSRUTA SAMHITA - A MEDICO-SURGICAL TEACHING COMPENDIUM
BY SUSRUTA OF ANCIENT INDIA’, Journal of Urology. doi: 10.1016/j.juro.2014.02.1724.
Deogade, S., Gupta, P. and Ariga, P. (2018) ‘Effect of monopoly-coating agent on the surface roughness of a tissue conditioner subjected to cleansing and disinfection: A Contact Profilometric In vitro study’, Contemporary Clinical Dentistry, p. 122. doi: 10.4103/ccd.ccd_112_18.
Dua, K. et al. (2019) ‘The potential of siRNA based drug delivery in respiratory disorders: Recent advances and progress’, Drug development research, 80(6), pp. 714–730.
Duraisamy, R. et al. (2019) ‘Compatibility of Nonoriginal Abutments With Implants: Evaluation of Microgap at the Implant-Abutment Interface, With Original and Nonoriginal Abutments’, Implant dentistry, 28(3), pp. 289–295.
Dyavanagoudar, S. N. (2009) ‘Oral Submucous Fibrosis: Review on Etiopathogenesis’, Journal of Cancer Science & Therapy, pp. 072–077. doi: 10.4172/1948-5956.1000011.
Ezhilarasan, D. (2018) ‘Oxidative stress is bane in chronic liver diseases: Clinical and experimental perspective’, Arab journal of gastroenterology: the official publication of the Pan-Arab Association of Gastroenterology, 19(2), pp. 56–64.
Ezhilarasan, D., Apoorva, V. S. and Ashok Vardhan, N. (2019) ‘Syzygium cumini extract induced reactive oxygen species-mediated apoptosis in human oral squamous carcinoma cells’, Journal of oral pathology & medicine: official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 48(2), pp. 115–121.
Ezhilarasan, D., Sokal, E. and Najimi, M. (2018) ‘Hepatic fibrosis: It is time to go with hepatic stellate cell-specific therapeutic targets’, Hepatobiliary & pancreatic diseases international: HBPD INT, 17(3),
pp. 192–197.
Gheena, S. and Ezhilarasan, D. (2019) ‘Syringic acid triggers reactive oxygen species-mediated cytotoxicity in HepG2 cells’, Human & experimental toxicology, 38(6), pp. 694–702.
Gomathi, A. C. et al. (2020) ‘Anticancer activity of silver nanoparticles synthesized using aqueous fruit shell extract of Tamarindus indica on MCF-7 human breast cancer cell line’, Journal of Drug Delivery Science and Technology, p. 101376. doi: 10.1016/j.jddst.2019.101376.
Haque, M. F. et al. (1998) ‘IMMUNOLOCALIZATION OF CYTOKINES AND GROWTH FACTORS IN ORAL SUBMUCOUS FIBROSIS’, Cytokine, pp. 713–719. doi: 10.1006/cyto.1997.0342.
Haque, M. F. et al. (2000) ‘Oral submucous fibrosis patients have altered levels of cytokine production’, Journal of oral pathology & medicine: official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 29(3), pp. 123–128.
Hattab, F. N. and Amin, W. M. (2005) ‘Papillon-Lefèvre syndrome with albinism: A review of the literature and report of 2 brothers’, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, pp. 709–716. doi: 10.1016/j.tripleo.2004.08.030.
Hazarey, V. K. et al. (2007) ‘Oral submucous fibrosis: study of 1000 cases from central India’, Journal of oral pathology & medicine: official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 36(1), pp. 12–17.
Jagadish, R., Jagadish, P. and Mehta, D. (2012) ‘Oral and periodontal manifestations associated with systemic sclerosis: A case series and review’, Journal of Indian Society of Periodontology, p. 271. doi: 10.4103/0972-124x.99275.
Jeevanandan, G. and Govindaraju, L. (2018) ‘Clinical comparison of Kedo-S paediatric rotary files vs manual instrumentation for root canal preparation in primary molars: a double blinded randomised clinical trial’, European Archives of Paediatric Dentistry, pp. 273–278. doi: 10.1007/s40368-018-0356-6.
Jeng, J. H., Chang, M. C. and Hahn, L. J. (2001) ‘Role of areca nut in betel quid-associated chemical carcinogenesis: current awareness and future perspectives’, Oral Oncology, pp. 477–492. doi: 10.1016/s1368-8375(01)00003-3.
Jesudasan, J. S., Abdul Wahab, P. U. and Muthu Sekhar, M. R. (2015) ‘Effectiveness of 0.2% chlorhexidine gel and a eugenol-based paste on postoperative alveolar osteitis in patients having third molars extracted: a randomised controlled clinical trial’, British Journal of Oral and Maxillofacial Surgery, pp. 826–830. doi: 10.1016/j.bjoms.2015.06.022.
J, P. C. et al. (2018) ‘Prevalence and measurement of anterior loop of the mandibular canal using CBCT: A cross sectional study’, Clinical implant dentistry and related research, 20(4), pp. 531–534.
Karthik, H. et al. (2012) ‘Role of hemoglobin and serum iron in oral submucous fibrosis: a clinical study’,
TheScientificWorldJournal, 2012, p. 254013.
Kumar, S. (2017) ‘KNOWLEDGE, ATTITUDE AND AWARENESS OF DENTAL UNDERGRADUATE STUDENTS REGARDING HIV/AIDS PATIENTS’, Asian Journal of
Pharmaceutical and Clinical Research, p. 175. doi: 10.22159/ajpcr.2017.v10i5.17277.
Kumar, S. and Rahman, R. (2017) ‘KNOWLEDGE, AWARENESS, AND PRACTICES REGARDING BIOMEDICAL WASTE MANAGEMENT AMONG UNDERGRADUATE DENTAL STUDENTS’,
Asian Journal of Pharmaceutical and Clinical Research, p. 341. doi: 10.22159/ajpcr.2017.v10i8.19101.
Kumar, S. and Sneha, S. (2016) ‘KNOWLEDGE AND AWARENESS REGARDING ANTIBIOTIC PROPHYLAXIS FOR INFECTIVE ENDOCARDITIS AMONG UNDERGRADUATE DENTAL
STUDENTS’, Asian Journal of Pharmaceutical and Clinical Research, p. 154. doi: 10.22159/ajpcr.2016.v9s2.13405.
Malli Sureshbabu, N. et al. (2019) ‘Concentrated Growth Factors as an Ingenious Biomaterial in Regeneration of Bony Defects after Periapical Surgery: A Report of Two Cases’, Case reports in dentistry, 2019, p. 7046203.
Marimuthu, M. et al. (2017) ‘EXPRESSION ANALYSIS OF CANONICAL WNT PATHWAY GENES IN ORAL SQUAMOUS CELL CARCINOMA AND THEIR POSSIBLE ROLE AS BIOMARKERS’,
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, p. e197. doi: 10.1016/j.oooo.2017.05.496.
Mathew, M. G. et al. (2020) ‘Evaluation of adhesion of Streptococcus mutans, plaque accumulation on zirconia and stainless steel crowns, and surrounding gingival inflammation in primary …’, Clinical oral investigations. Available at: https://link.springer.com/article/10.1007/s00784-020-03204-9.
Mehta, M. et al. (2019) ‘Oligonucleotide therapy: An emerging focus area for drug delivery in chronic inflammatory respiratory diseases’, Chemico-biological interactions, 308, pp. 206–215.
Menon, S. et al. (2018) ‘Selenium nanoparticles: A potent chemotherapeutic agent and an elucidation of its mechanism’, Colloids and Surfaces B: Biointerfaces, pp. 280–292. doi: 10.1016/j.colsurfb.2018.06.006.
Mp, S. K. (2017) ‘Relationship between dental anxiety and pain experience during dental extractions’, Asian J Pharm Clin Res. Available at: https://pdfs.semanticscholar.org/f024/7b95077e4a0bb861eb9b8b815893f19758d6.pdf.
Panchal, V., Jeevanandan, G. and Subramanian, E. M. G. (2019) ‘Comparison of post-operative pain after root canal instrumentation with hand K-files, H-files and rotary Kedo-S files in primary teeth: a randomised clinical trial’, European archives of paediatric dentistry: official journal of the European Academy of Paediatric Dentistry, 20(5), pp. 467–472.
Patil, N. P. et al. (2017) ‘Study of Fingertip Patterns in Oral Submucus Fibrosis Associated with Chronic Gutkha Chewing’, Indian Journal of Anatomy, pp. 234–240. doi: 10.21088/ija.2320.0022.6217.27.
Patturaja, K. and Pradeep, D. (2016) ‘Awareness of Basic Dental Procedure among General Population’,
Research Journal of Pharmacy and Technology, 9(9), pp. 1349–1351.
Paymaster, J. C. (1956) ‘Cancer of the buccal mucosa.A clinical study of 650 cases in Indian patients’,
Cancer, pp. 431–435. doi: 3.0.co;2-t">10.1002/1097-0142(195605/06)9:3<431::aid cncr2820090302>3.0.co;2-t.
Pc, J., Marimuthu, T. and Devadoss, P. (2018) ‘Prevalence and measurement of anterior loop of the mandibular canal using CBCT: A cross sectional study’, Clinical implant dentistry and related research. Available at: https://europepmc.org/article/med/29624863.
Prabakar, J. et al. (2018) ‘Comparative Evaluation of Retention, Cariostatic Effect and Discoloration of Conventional and Hydrophilic Sealants - A Single Blinded Randomized Split Mouth Clinical Trial’, Contemporary clinical dentistry, 9(Suppl 2), pp. S233–S239.
Praveen, G. et al. (2015) ‘Innovative dual impression technique for patients with atrophia idiopathica mucosa oris’, The Journal of Indian Prosthodontic Society, p. 98. doi: 10.4103/0972-4052.155029.
Rajendran, R. et al. (2019) ‘Comparative Evaluation of Remineralizing Potential of a Paste Containing Bioactive Glass and a Topical Cream Containing Casein Phosphopeptide-Amorphous Calcium Phosphate: An in Vitro Study’, Pesquisa Brasileira em Odontopediatria e Clínica Integrada, pp. 1–10. doi: 10.4034/pboci.2019.191.61.
Rajeshkumar, S. et al. (2018) ‘Biosynthesis of zinc oxide nanoparticles usingMangifera indica leaves and evaluation of their antioxidant and cytotoxic properties in lung cancer (A549) cells’, Enzyme and microbial technology, 117, pp. 91–95.
Rajeshkumar, S. et al. (2019) ‘Antibacterial and antioxidant potential of biosynthesized copper nanoparticles mediated through Cissus arnotiana plant extract’, Journal of photochemistry and photobiology. B, Biology, 197, p. 111531.
Ramadurai, N. et al. (2019) ‘Effectiveness of 2% Articaine as an anesthetic agent in children: randomized controlled trial’, Clinical oral investigations, 23(9), pp. 3543–3550.
Ramakrishnan, M., Dhanalakshmi, R. and Subramanian, E. M. G. (2019) ‘Survival rate of different fixed posterior space maintainers used in Paediatric Dentistry - A systematic review’, The Saudi dental journal, 31(2), pp. 165–172.
Ramesh, A. et al. (2018) ‘Comparative estimation of sulfiredoxin levels between chronic periodontitis and healthy patients - A case-control study’, Journal of periodontology, 89(10), pp. 1241–1248.
Ranganathan, K. et al. (2008) ‘Oral lesions and conditions associated with human immunodeficiency virus infection in 300 south Indian patients’, Oral Diseases, pp. 152–157. doi: 10.1111/j.1601- 0825.2000.tb00326.x.
Samuel, S. R., Acharya, S. and Rao, J. C. (2020) ‘School Interventions-based Prevention of Early- Childhood Caries among 3-5-year-old children from very low socioeconomic status: Two-year randomized trial’, Journal of public health dentistry, 80(1), pp. 51–60.
Sharma, P. et al. (2019) ‘Emerging trends in the novel drug delivery approaches for the treatment of lung cancer’, Chemico-biological interactions, 309, p. 108720.
Shiau, Y. Y. and Kwan, H. W. (1979) ‘Submucous fibrosis in Taiwan’, Oral surgery, oral medicine, and oral pathology, 47(5), pp. 453–457.
Sridharan, G. et al. (2019) ‘Evaluation of salivary metabolomics in oral leukoplakia and oral squamous cell carcinoma’, Journal of oral pathology & medicine: official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 48(4), pp. 299–306.
Sweta, V. R., Abhinav, R. P. and Ramesh, A. (2019) ‘Role of Virtual Reality in Pain Perception of Patients Following the Administration of Local Anesthesia’, Annals of maxillofacial surgery, 9(1), pp. 110–113.
Tilakaratne, W. M. et al. (2006) ‘Oral submucous fibrosis: review on aetiology and pathogenesis’, Oral oncology, 42(6), pp. 561–568.
Varghese, S. S., Ramesh, A. and Veeraiyan, D. N. (2019) ‘Blended Module-Based Teaching in Biostatistics and Research Methodology: A Retrospective Study with Postgraduate Dental Students’, Journal of dental education, 83(4), pp. 445–450.
Vijayashree Priyadharsini, J. (2019) ‘In silico validation of the non-antibiotic drugs acetaminophen and ibuprofen as antibacterial agents against red complex pathogens’, Journal of periodontology, 90(12), pp. 1441–1448.
Vishnu Prasad, S. et al. (2018) ‘Report on oral health status and treatment needs of 5-15 years old children with sensory deficits in Chennai, India’, Special care in dentistry: official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry, 38(1), pp. 58–59.
Wahab, P. U. A. et al. (2018) ‘Scalpel Versus Diathermy in Wound Healing After Mucosal Incisions: A Split-Mouth Study’, Journal of oral and maxillofacial surgery: official journal of the American Association of Oral and Maxillofacial Surgeons, 76(6), pp. 1160–1164.
Yen, D. J. C. (1982) ‘Surgical treatment of submucous fibrosis’, Oral Surgery, Oral Medicine, Oral Pathology, pp. 269–272. doi: 10.1016/0030-4220(82)90094-9.
Downloads
Published
How to Cite
Issue
Section
License
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation .
No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.
