Insilico Interaction Of Selected Terpenoids Against Oral Biofilm (Streptococcus Mutans) Drug Targets.
Journal of Contemporary Issues in Business and Government,
2021, Volume 27, Issue 2, Pages 4357-4359
AbstractAim: The aim is to analyse the In Silico interaction of selected terpenoids against streptococcus mutans drug targets.
Materials And Methods: • Retrieval of protein using ligand structure.
• Molecular docking using iGemdock.
Results: From this study it is evident that docking is significant in Neptalactone. It has the highest fitness (-48.4), lowest VDW (-32.02), and H bond equal to standard inhibitor (-16.33).
Conclusion:The compound Neptalactone with the highest docking score is most efficient in blocking biofilm formation when compared to other compounds.
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