Journal of Contemporary Issues in Business and Government

Turmeric and Its Pharmacological Properties- A Review

Document Type : Research Article

Authors

1 Department of Physiology,Saveetha Dental College and hospitals,Saveetha Institute of Medical and Technical Sciences, Saveetha University,Chennai.

2 Senior Lecturer,Department of Physiology,Saveetha Dental college and hospitals,Saveetha Institute of Medical and Technical Sciences, Saveetha university,Chennai.

Abstract

Turmeric is a flowering plant, Curcuma longa of the ginger family, Zingiberaceae, the roots of which are used in cooking. The plant is a perennial, rhizomatous, herbaceous plant local to the Indian subcontinent and Southeast Asia, that calls for temperatures between 20 and 30 °C (68 and 86 °F) and a large amount of annual rainfall to thrive. Plants are gathered each year for their rhizomes, a few for propagation in the following season and some for consumption. This is a review based study on topic turmeric over viral diseases, articles based on turmeric were referred completely which were taken from “pub med”, “google scholar”, PMC. Around 20-25 articles were referred. Other articles which have done a study on medicinal and pharmacological properties of turmeric are also compared. Hence turmeric has a wide range of biological activities which can be used for preparation of various formulations for the treatment of various conditions.

Keywords

Main Subjects

References
  1. Abigail et al. (2019) ‘Evaluation of Muscular Endurance among Dentists’, Indian Journal of Public Health Research & Development, p. 258. doi: 10.5958/0976-5506.2019.02808.0.
  2. Agarwal, S. et al. (2018) ‘Turmeric: isolation and synthesis of important biological molecules’, Synthesis of Medicinal Agents from Plants, pp. 105–125. doi: 10.1016/b978-0-08-102071-5.00005-2.
  3. Aggarwal, B. B. et al. (2013) ‘Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities: Identification of novel components of turmeric’, Molecular Nutrition & Food Research, pp. 1529–1542. doi: 10.1002/mnfr.201200838.
  4. Aggarwal, B. B. and Harikumar, K. B. (2009) ‘Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases’, The International Journal of Biochemistry & Cell Biology, pp. 40–59. doi: 10.1016/j.biocel.2008.06.010.
  5. Ali, M., Bagati, A. and Gupta, J. (2010) ‘ChemInform Abstract: Synthesis and Antiinflammatory Activity of Some Curcumin Analogues’, ChemInform, p. no–no. doi: 10.1002/chin.199552195.
  6. Ammon, H. et al. (1992) ‘Curcumin: A Potent Inhibitor of Leukotriene B4Formation in Rat Peritoneal Polymorphonuclear Neutrophils (PMNL)’, Planta Medica, pp. 226–226. doi: 10.1055/s-2006-961438.
  7. Anggakusuma et al. (2014) ‘Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells’, Gut, 63(7), pp. 1137–1149.
  8. Ara�jo, M. C. P., Antunes, L. M. G. and Takahashi, C. S. (2001) ‘Protective effect of thiourea, a hydroxyl-radical scavenger, on curcumin-induced chromosomal aberrations in an in vitro mammalian cell system’, Teratogenesis, Carcinogenesis, and Mutagenesis, pp. 175–180. doi: 3.0.co;2-v">10.1002/1520-6866(2001)21:2<175::aid-tcm6>3.0.co;2-v.
  9. Baheerati, M. M. and Gayatri Devi, R. (2018) ‘Obesity in relation to Infertility’, Research Journal of Pharmacy and Technology, p. 3183. doi: 10.5958/0974-360x.2018.00585.1.
  10. Balachandran, K. and Stebbing, J. (2016) ‘Turmeric: a spice for life?’, The Lancet Oncology, p. 1639. doi: 10.1016/s1470-2045(16)30587-3.
  11. Choudhari, S. and Jothipriya, M. A. (2016) ‘Non-alcoholic fatty liver disease’, Research Journal of Pharmacy and Technology, p. 1782. doi: 10.5958/0974-360x.2016.00360.7.
  12. Clercq, E. de, de Clercq, E. and Herdewijn, P. (2005) ‘Strategies in the Design of Antiviral Drugs’, Drug Discovery Handbook, pp. 1135–1190. doi: 10.1002/0471728780.ch25.
  13. Dairaku, I. et al. (2010) ‘Inhibitory effect of curcumin on IMP dehydrogenase, the target for anticancer and antiviral chemotherapy agents’, Bioscience, biotechnology, and biochemistry, 74(1), pp. 185–187.
  14. Dave, P. H. and Preetha (2016) ‘Pathogenesis and Novel Drug for Treatment of Asthma-A Review’, Research Journal of Pharmacy and Technology, p. 1519. doi: 10.5958/0974-360x.2016.00297.3.
  15. David et al. (2019) ‘Physical Fitness among the Dental Physician, Dental Undergraduates and Postgraduates Students’, Indian Journal of Public Health Research & Development, p. 223. doi: 10.5958/0976-5506.2019.02801.8.
  16. Deogade, S., Gupta, P. and Ariga, P. (2018) ‘Effect of monopoly-coating agent on the surface roughness of a tissue conditioner subjected to cleansing and disinfection: A Contact Profilometric In vitro study’, Contemporary Clinical Dentistry, p. 122. doi: 10.4103/ccd.ccd_112_18.
  17. Dua, K. et al. (2019) ‘The potential of siRNA based drug delivery in respiratory disorders: Recent advances and progress’, Drug development research, 80(6), pp. 714–730.
  18. Duraisamy, R. et al. (2019) ‘Compatibility of Nonoriginal Abutments With Implants: Evaluation of Microgap at the Implant-Abutment Interface, With Original and Nonoriginal Abutments’, Implant dentistry, 28(3), pp. 289–295.
  19. Ezhilarasan, D. (2018) ‘Oxidative stress is bane in chronic liver diseases: Clinical and experimental perspective’, Arab journal of gastroenterology: the official publication of the Pan-Arab Association of Gastroenterology, 19(2), pp. 56–64.
  20. Ezhilarasan, D., Apoorva, V. S. and Ashok Vardhan, N. (2019) ‘Syzygium cumini extract induced reactive oxygen species-mediated apoptosis in human oral squamous carcinoma cells’, Journal of oral pathology & medicine: official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 48(2), pp. 115–121.
  21. Ezhilarasan, D., Sokal, E. and Najimi, M. (2018) ‘Hepatic fibrosis: It is time to go with hepatic stellate cell-specific therapeutic targets’, Hepatobiliary & pancreatic diseases international: HBPD INT, 17(3), pp. 192–197.
  22. Fathima, F. and Preetha, P. (2016) ‘EVALUATION OF THYROID FUNCTION TEST IN OBESE PATIENTS’, Asian Journal of Pharmaceutical and Clinical Research, p. 353. doi: 10.22159/ajpcr.2016.v9s3.12959.
  23. Gheena, S. and Ezhilarasan, D. (2019) ‘Syringic acid triggers reactive oxygen species-mediated cytotoxicity in HepG2 cells’, Human & experimental toxicology, 38(6), pp. 694–702.
  24. Gomathi, A. C. et al. (2020) ‘Anticancer activity of silver nanoparticles synthesized using aqueous fruit shell extract of Tamarindus indica on MCF-7 human breast cancer cell line’, Journal of Drug Delivery Science and Technology, p. 101376. doi: 10.1016/j.jddst.2019.101376.
  25. Gul, P. and Bakht, J. (2015) ‘Antimicrobial activity of turmeric extract and its potential use in food industry’, Journal of Food Science and Technology, pp. 2272–2279. doi: 10.1007/s13197-013-1195-4.
  26. Harsha, L. et al. (2015) ‘Systemic Approach to Management of Neonatal Jaundice and Prevention of Kernicterus’, Research Journal of Pharmacy and Technology, p. 1087. doi: 10.5958/0974-360x.2015.00189.4.
  27. Iyer, P. K., Gayatri Devi, R. and Jothi Priya, A. (2019) ‘A Survey Study on Causes, Treatment and Prevention of Onychocryptosis’, Indian Journal of Public Health Research & Development, p. 807. doi: 10.5958/0976-5506.2019.01990.9.
  28. Jassim, S. A. A. and Naji, M. A. (2003) ‘Novel antiviral agents: a medicinal plant perspective’, Journal of applied microbiology, 95(3), pp. 412–427.
  29. Jeevanandan, G. and Govindaraju, L. (2018) ‘Clinical comparison of Kedo-S paediatric rotary files vs manual instrumentation for root canal preparation in primary molars: a double blinded randomised clinical trial’, European Archives of Paediatric Dentistry, pp. 273–278. doi: 10.1007/s40368-018-0356-6.
  30. J, P. C. et al. (2018) ‘Prevalence and measurement of anterior loop of the mandibular canal using CBCT: A cross sectional study’, Clinical implant dentistry and related research, 20(4), pp. 531–534.
  31. Juglal, S., Govinden, R. and Odhav, B. (2002) ‘Spice Oils for the Control of Co-Occurring Mycotoxin-Producing Fungi’, Journal of Food Protection, pp. 683–687. doi: 10.4315/0362-028x-65.4.683.
  32. Krishnaswamy, K. (2009) Turmeric: The Salt of the Orient is the Spice of Life. Allied Publishers.
  33. Kumar, R. et al. (2016) ‘STUDY OF INHIBITORY EFFECT OF EXTRACT OF TURMERIC (CURCUMA LONGA) ON STAPHYLOCOCCUS AUREUS’, International Journal of Therapeutic Applications, pp. 38–40. doi: 10.20530/ijta_32_38-40.
  34. Kumar, S. et al. (2001) ‘Syntheses of Curcumin Bioconjugates and Study of Their Antibacterial Activities against beta-Lactamase-Producing Microorganisms’, Bioconjugate chemistry, 12(4), pp. 464–469.
  35. Kuttan, R. et al. (1985) ‘Potential anticancer activity of turmeric (Curcuma longa)’, Cancer Letters, pp. 197–202. doi: 10.1016/0304-3835(85)90159-4.
  36. Lemoine, M., Nayagam, S. and Thursz, M. (2013) ‘Viral hepatitis in resource-limited countries and access to antiviral therapies: current and future challenges’, Future virology, 8(4), pp. 371–380.
  37. Mahour, S. S. et al. (2018) ‘Antibacterial Property of Hot and Cold Extracted Turmeric Extract: An In-Vitro Study’, International Journal of Current Microbiology and Applied Sciences, pp. 3147–3151. doi: 10.20546/ijcmas.2018.710.364.
  38. Majeed, M., Badmaev, V. and Murray, F. (1999) Turmeric and the Healing Curcuminoids. McGraw Hill Professional.
  39. Malli Sureshbabu, N. et al. (2019) ‘Concentrated Growth Factors as an Ingenious Biomaterial in Regeneration of Bony Defects after Periapical Surgery: A Report of Two Cases’, Case reports in dentistry, 2019, p. 7046203.
  40. Mathew, M. G. et al. (2020) ‘Evaluation of adhesion of Streptococcus mutans, plaque accumulation on zirconia and stainless steel crowns, and surrounding gingival inflammation in primary …’, Clinical oral investigations. Available at: https://link.springer.com/article/10.1007/s00784-020-03204-9.
  41. Mehta, M. et al. (2019) ‘Oligonucleotide therapy: An emerging focus area for drug delivery in chronic inflammatory respiratory diseases’, Chemico-biological interactions, 308, pp. 206–215.
  42. Menon, S. et al. (2018) ‘Selenium nanoparticles: A potent chemotherapeutic agent and an elucidation of its mechanism’, Colloids and Surfaces B: Biointerfaces, pp. 280–292. doi: 10.1016/j.colsurfb.2018.06.006.
  43. Mizushina, Y. et al. (2007) ‘Study on the Molecular Structure and Bio-Activity (DNA Polymerase Inhibitory Activity, Anti-Inflammatory Activity and Anti-Oxidant Activity) Relationship of Curcumin Derivatives’, Current Bioactive Compounds, pp. 171–177. doi: 10.2174/157340707781695488.
  44. Moghadamtousi, S. Z. et al. (2013) ‘Loranthus micranthusLinn.: Biological Activities and Phytochemistry’, Evidence-Based Complementary and Alternative Medicine, pp. 1–9. doi: 10.1155/2013/273712.
  45. Nair, K. P. (2019a) ‘The Botany of Turmeric’, Turmeric (Curcuma longa L.) and Ginger (Zingiber officinale Rosc.) - World’s Invaluable Medicinal Spices, pp. 7–35. doi: 10.1007/978-3-030-29189-1_2.
  46. Nair, K. P. (2019b) Turmeric (Curcuma longa L.) and Ginger (Zingiber officinale Rosc.) - World’s Invaluable Medicinal Spices: The Agronomy and Economy of Turmeric and Ginger. Springer Nature.
  47. Nair, K. P. (2019c) ‘Turmeric in Ayurveda’, Turmeric (Curcuma longa L.) and Ginger (Zingiber officinale Rosc.) - World’s Invaluable Medicinal Spices, pp. 235–243. doi: 10.1007/978-3-030-29189-1_14.
  48. Nair, K. P. (2019d) ‘Turmeric: Origin and History’, Turmeric (Curcuma longa L.) and Ginger (Zingiber officinale Rosc.) - World’s Invaluable Medicinal Spices, pp. 1–6. doi: 10.1007/978-3-030-29189-1_1.
  49. Nawab, A. et al. (2020) ‘Dietary curcumin supplementation effects on blood immunological profile and liver enzymatic activity of laying hens after exposure to high temperature conditions’, Journal of thermal biology, 90, p. 102573.
  50. Oghenejobo, M. (2017) ‘Antibacterial Evaluation, Phytochemical Screening and Ascorbic Acid Assay of Turmeric (Curcuma longa)’, MOJ Bioequivalence & Bioavailability. doi: 10.15406/mojbb.2017.04.00063.
  51. Omosa, L. K., Midiwo, J. O. and Kuete, V. (2017) ‘Curcuma longa’, Medicinal Spices and Vegetables from Africa, pp. 425–435. doi: 10.1016/b978-0-12-809286-6.00019-4.
  52. Panchal, V., Jeevanandan, G. and Subramanian, E. M. G. (2019) ‘Comparison of post-operative pain after root canal instrumentation with hand K-files, H-files and rotary Kedo-S files in primary teeth: a randomised clinical trial’, European archives of paediatric dentistry: official journal of the European Academy of Paediatric Dentistry, 20(5), pp. 467–472.
  53. Parveen, Z. et al. (2013) ‘Composition and Antimicrobial Activity of the Essential Oil from Leaves of Curcuma longa L. Kasur Variety’, Indian Journal of Pharmaceutical Sciences, p. 117. doi: 10.4103/0250-474x.113544.
  54. Pc, J., Marimuthu, T. and Devadoss, P. (2018) ‘Prevalence and measurement of anterior loop of the mandibular canal using CBCT: A cross sectional study’, Clinical implant dentistry and related research. Available at: https://europepmc.org/article/med/29624863.
  55. Prabakar, J. et al. (2018) ‘Comparative Evaluation of Retention, Cariostatic Effect and Discoloration of Conventional and Hydrophilic Sealants - A Single Blinded Randomized Split Mouth Clinical Trial’, Contemporary clinical dentistry, 9(Suppl 2), pp. S233–S239.
  56. Rajendran, R. et al. (2019) ‘Comparative Evaluation of Remineralizing Potential of a Paste Containing Bioactive Glass and a Topical Cream Containing Casein Phosphopeptide-Amorphous Calcium Phosphate: An in Vitro Study’, Pesquisa Brasileira em Odontopediatria e Clínica Integrada, pp. 1–10. doi: 10.4034/pboci.2019.191.61.
  57. Rajeshkumar, S. et al. (2018) ‘Biosynthesis of zinc oxide nanoparticles usingMangifera indica leaves and evaluation of their antioxidant and cytotoxic properties in lung cancer (A549) cells’, Enzyme and microbial technology, 117, pp. 91–95.
  58. Rajeshkumar, S. et al. (2019) ‘Antibacterial and antioxidant potential of biosynthesized copper nanoparticles mediated through Cissus arnotiana plant extract’, Journal of photochemistry and photobiology. B, Biology, 197, p. 111531.
  59. Ramadurai, N. et al. (2019) ‘Effectiveness of 2% Articaine as an anesthetic agent in children: randomized controlled trial’, Clinical oral investigations, 23(9), pp. 3543–3550.
  60. Ramakrishnan, M., Dhanalakshmi, R. and Subramanian, E. M. G. (2019) ‘Survival rate of different fixed posterior space maintainers used in Paediatric Dentistry - A systematic review’, The Saudi dental journal, 31(2), pp. 165–172.
  61. Ramesh, A. et al. (2018) ‘Comparative estimation of sulfiredoxin levels between chronic periodontitis and healthy patients - A case-control study’, Journal of periodontology, 89(10), pp. 1241–1248.
  62. Renuka, S. and Sethu, G. (2015) ‘Regeneration after Myocardial Infarction’, Research Journal of Pharmacy and Technology, p. 738. doi: 10.5958/0974-360x.2015.00117.1.
  63. R, G. D. and Sethu, G. (2018) ‘EVALUATION OF ADENOIDS BY ORONASAL AND NASAL SPIROMETRY’, Asian Journal of Pharmaceutical and Clinical Research, p. 272. doi: 10.22159/ajpcr.2018.v11i10.27365.
  64. Rj, I. and R, G. D. (2016) ‘Role of environmental factors on sleep patterns of different age groups’, Asian Journal of Pharmaceutical and Clinical Research, p. 124. doi: 10.22159/ajpcr.2016.v9i6.13832.
  65. Samuel, A. R. and Devi, M. G. (2015) ‘Geographical distribution and occurrence of Endemic Goitre’, Research Journal of Pharmacy and Technology, p. 973. doi: 10.5958/0974-360x.2015.00162.6.
  66. Samuel, S. R., Acharya, S. and Rao, J. C. (2020) ‘School Interventions-based Prevention of Early-Childhood Caries among 3-5-year-old children from very low socioeconomic status: Two-year randomized trial’, Journal of public health dentistry, 80(1), pp. 51–60.
  67. Schaefer, E. W. et al. (2020) ‘Influence of turmeric incorporation on physicochemical, antimicrobial and mechanical properties of the cornstarch and chitosan films’, International journal of biological macromolecules, 148, pp. 342–350.
  68. Sharma, O. P. (1976) ‘Antioxidant activity of curcumin and related compounds’, Biochemical Pharmacology, pp. 1811–1812. doi: 10.1016/0006-2952(76)90421-4.
  69. Sharma, P. et al. (2019) ‘Emerging trends in the novel drug delivery approaches for the treatment of lung cancer’, Chemico-biological interactions, 309, p. 108720.
  70. Shruthi, M. and Preetha, S. (2018) ‘Effect of Simple Tongue Exercises in Habitual Snorers’, Research Journal of Pharmacy and Technology, p. 3614. doi: 10.5958/0974-360x.2018.00665.0.
  71. Sridharan, G. et al. (2019) ‘Evaluation of salivary metabolomics in oral leukoplakia and oral squamous cell carcinoma’, Journal of oral pathology & medicine: official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 48(4), pp. 299–306.
  72. Swathy, S. and Gowri Sethu, V. (2015) ‘Acupuncture and lower back pain’, Research Journal of Pharmacy and Technology, p. 991. doi: 10.5958/0974-360x.2015.00165.1.
  73. Taylor, G. (2015) Turmeric: Nutritional Properties, Uses and Potential Benefits.
  74. Thomas-Eapen, N. E. (2009) ‘Turmeric: The Intriguing Yellow Spice With Medicinal Properties’, EXPLORE, pp. 114–115. doi: 10.1016/j.explore.2008.12.008.
  75. Timothy, C. N., Gayatri Devi, R. and Jothi Priya, A. (2019) ‘Evaluation of Peak Expiratory Flow Rate (PEFR) in Pet Owners’, Indian Journal of Public Health Research & Development, p. 803. doi: 10.5958/0976-5506.2019.01989.2.
  76. Tomei, L. et al. (2005) ‘HCV antiviral resistance: the impact of in vitro studies on the development of antiviral agents targeting the viral NS5B polymerase’, Antiviral chemistry & chemotherapy, 16(4), pp. 225–245.
  77. Varghese, S. S., Ramesh, A. and Veeraiyan, D. N. (2019) ‘Blended Module-Based Teaching in Biostatistics and Research Methodology: A Retrospective Study with Postgraduate Dental Students’, Journal of dental education, 83(4), pp. 445–450.
  78. Vijayashree Priyadharsini, J. (2019) ‘In silico validation of the non-antibiotic drugs acetaminophen and ibuprofen as antibacterial agents against red complex pathogens’, Journal of periodontology, 90(12), pp. 1441–1448.
  79. Vishnu Prasad, S. et al. (2018) ‘Report on oral health status and treatment needs of 5-15 years old children with sensory deficits in Chennai, India’, Special care in dentistry: official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry, 38(1), pp. 58–59.
  80. Wahab, P. U. A. et al. (2018) ‘Scalpel Versus Diathermy in Wound Healing After Mucosal Incisions: A Split-Mouth Study’, Journal of oral and maxillofacial surgery: official journal of the American Association of Oral and Maxillofacial Surgeons, 76(6), pp. 1160–1164.

 

Journal of Contemporary Issues in Business and Government
Volume 27, Issue 2
February 2021
Page 3269-3275
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